Substitol causes its users to develop a high physical and psychological dependence on it. The brain’s chemistry and receptors react to this substance as well and become interrupted.

As soon as substitol stops circulating the body, withdrawal symptoms can start, which is usually 6-12 hours after the last dose. The first symptoms include sweating, tearing up, yawning and a runny nose. After 48-72 hours a person might go through the following: goosebumps, chills, high blood pressure and increased heart rate, irritability, insomnia, anxiety, restlessness, muscle pain, nausea, stomach pain, diarrhea, vomiting, tremors, sneezing, loss of appetite, depression and strong drug cravings.

Subutex withdrawal

Dealing with emotion and psychological effects can be also very difficult, which is why the person should be closely monitored and not be left unsupervised.

Going through a substitol withdrawal process is extremely difficult without professional help and many factors need to be taken into a consideration. Such as duration and amount of drug use, family history, co-occurring disorders, polydrug abuse (if patient was using substitol alongside other substances), environmental factors etc.